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KMID : 0356920110610060465
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Korean Journal of Anesthesiology
2011 Volume.61 No. 6 p.465 ~ p.469
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Dilution and slow injection reduces the incidence of rocuronium-induced withdrawal movements in children
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Shin Young-Hee
Kim Chung-Su
Lee Jong-Hwan
Sim Woo-Seog
Ko Sang-Wook
Cho Hyun-Sung
Jeong Hui-Yeon
Lee Hye-Won
Kim Sang-Hyun
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Abstract
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Background: The aim of this study was to evaluate whether slow injection of diluted rocuronium could reduce rocuronium-induced withdrawal movements effectively in children.
Methods: After loss of consciousness, rocuronium 0.6 mg/kg was administered into 171 children according to the pre-assigned groups as follows: Group CF, injection of non-diluted rocuronium over 5 seconds; Group CS, injection of non-diluted rocuronium over 1 minute; Group DF, injection of diluted rocuronium (10 times) over 5 seconds; Group DS, injection of diluted rocuronium over 1 minute. An investigator who was blind to the injection techniques recorded patient movements followed by rocuronium injection.
Results: The incidence of withdrawal movement in Group CF was highest among the groups (all P < 0.0001). Moreover, withdrawal movement was less frequently observed in Group DS than in Groups CS and DF (P = 0.021 and P = 0.007, respectively).
Conclusions: Slow injection of diluted rocuronium reduced the incidence of withdrawal movements in children.
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KEYWORD
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Child, Injections, Intravenous, Movement, Pain, Rocuronium
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